Background:Mean platelet volum to platelet count (MPV/Plt) ratio (MPR) is a new predictor of mortality in critical patients with COVID-19 infection in intensive care unit (ICU). Objective:To retrospectively examine the laboratory predictors of mortality among COVID-19 patients. Materials and Methods:A total of 106 patients with COVID-19 in ICU were enrolled in the study.The medical records of the patients and the electronic patient monitoring system were retrospectively analyzed. Results:The Interleukin-6, C-reactive protein (CRP), procalcitonin, leukocyte count, neutrophil count, neutrophil %, neutrophil count/lymphocyte count (NLR) and neutrophil count/albumin (NAR) ratio was significantly higher among nonsurvivors (p=0.0001, p=0.004, p=0.003, p=0.049, p=0.007, p=0.009, p=0.007 and p=0.0001; respectively).While the survivors had lower platelet distribution width, red blood cell distribution width, MPV and MPR (p=0.016, p=0.03, p=0.005 and p=0.049; respectively), hemoglobin, Plt, mean corpuscular hemoglobin concentration, lymphocyte % ve monocyte % were higher (p=0.022, p=0.033, p=0.042, p=0.008 and p=0.04; respectively). In the logistic regression analysis, five features, including high levels of CRP, procalsitonin, pro-BNP, MPR, and low level of plt were shown as mortality predictors for COVID-19 patients in ICU (p=0.045, p=0.025, p=0.017, p=0.027 and p=0.041; respectively). Conclusion:Mean platelet volum to platelet count ratio, NLR, NAR predict mortality in critical cases of COVID-19 which will contribute to early prediction, accurate diagnosis, and treatment to improve the prognosis of patients. Keywords: COVID-19, mortality, MPV, MPV/platelet ratio, NLR, platelet

Purpose: This study aimed to assess insulin resistance (IR) and diabetes risk levels using the FINDRISK noninvasive assessment tool in physicians from a tertiary care hospital. Methods: A cross-sectional study was carried out between February-April 2013 on 200 physicians working in a tertiary. Data was collected using the Finnish diabetes risk score (FINDRISK) tool, fasting blood glucose (FBG), and fasting insulin. The Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) was calculated. Results: Age was 25-45 years in 84.5% (n=169) of the physicians. Half of the participants were consultants, while the remaining were residents. Mean blood insulin, glucose, and HOMA-IR levels of the participants were 14.04±13.38 IU/mL, 93.55±10.11 mg/dl, and‎ 3.39±3.64, respectively. Most of the participants (58.0%, n=116) were males. The FINDRISK categories were low in 16.5% (n=32), mild in 36.5% (n=73), moderate in ‎‎23.5% (n=47), high in 18.5% (n=37), and very high in 5.5% (n=11). HOMA-IR was 2.6-33 in 49.5% (n=99), while impaired fasting glucose (IFG) was present in 24% (n=48) of the doctors. Majority of the physicians (77.5%, n=155) had a body mass index (BMI) of ≥ 25 kg/m2, did not exercise regularly (89.0%, n=178), did not consume daily vegetables and/or fruits (62.5%, n=125), and had diabetic relatives (72.0%, n=144). The risk of diabetes was higher among the consultants compared to the residents (p=0.001), which persisted even after controlling for age. Conclusions: Our findings suggest that the FINDRISK assessment may use in the screening of medical doctors for diabetes in Turkey. Diabetes is more prevalent among hypertensive physicians. Projects are needed to modify the reversible diabetes risk factors among medical doctors.