Aim: This study aimed to evaluate the attitudes of medical faculty sophomore students towards communication skills training module consists theory courses and simulated patient interviews. Methods: This study was planned in before-and-after intervention study and was carried out with 257 second-year medical students. The Communication Skills Attitude Scale (CSAS) were used for data collection. The scale was administered to the participants before the training (1), after the training (2), and after the simulated patient interviews (3). Results: The mean age of the students was 20.13±2.13 years, and 133 (51.8%) of them were female. PAS 1 and PAS 3 scores were 55.38±6.58 and 58.05±7.39, respectively, while NAS 1 and 3 scores were 30.25±4.49 and 28.88±4.96, respectively. PAS 3 was considerably higher than PAS 1 and 2 scores (p=0.037), while NAS 3 was significantly lower than NAS 1 and 2 scores (p=0.005). There was no difference between the positive and negative attitudes of females and males before the training. However, after the training, female’s positive scores significantly increased compared to men, and their negative scores decreased. Positive attitude scores of the female students increased after both the theory course and the simulated patient interviews. On the other hand, the negative attitude scores decreased significantly after the simulated patient interviews (p<0.05). Conclusion: Communication skills training improves students’ attitudes. In this improvement, the contribution of simulated patient interviews is more than theory instructions.