Aims: We conducted a meta-analysis of trials in when is prefectly to conduct a surgery for asymptomatic congenital pulmonary airway malformation (CPAM) in children. Methods: We searched the PubMed, Embase, Scopus and Cochrane Library databases to identify related articles published prior to April 2022 that conduct the surgery for asymptomatic congenital pulmonary airway malformation in children in different ages. Results: The results showed that operating the surgery between 3 months to 6 months old in patients can decrease the length of hospital stay. The younger the age of operation, the shorter the operation time. As for get rid of the ventilation as soon as possible and lower major complications, the surgery should be performed no more than 6 months old. Whereas, the chest tube duration as well as the number of deaths didn’t have statistically significant change. Conclusions: As for asymptomatic CPAM patients, we suggested that surgical treatment should be performed less than 6 months old.