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  • Vitoria De Godoy Saciloto,
  • Susana Claudete Costa,
  • Luciano da Silva,
  • Rachel Faverzani Magnago
Vitoria De Godoy Saciloto
Universidade do Sul de Santa Catarina

Corresponding Author:[email protected]

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Susana Claudete Costa
Universidade do Sul de Santa Catarina
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Luciano da Silva
Centro de Investigacion en Quimica Aplicada
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Rachel Faverzani Magnago
Universidade do Sul de Santa Catarina
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Biomaterials are important tools for the reconstruction of organs and tissues, and silica is widely used in these reconstruction technologies. Hence, a lexical and content analysis was carried out on articles on application of silica in biomaterials, based on a search in the Capes’ Journals Portal using the keywords “silica, biomedical, application, scaffold”, between the years 2009 and 2019. The 110 selected articles were analyzed using the IRaMuTeQ software, Word Cloud and Descending Hierarchical Classification (DHC). The words: “silica, cell, nanosilica, bone, material, scaffold and application” appear prominently in the Word Cloud and DHC indicating four classes: (1) physical characterization, (2) biomedicine applications, (3) engineering applications and (4) compatibility characterization. Thus, the analysis of DHC and Word Cloud showed that the main ways of using silica are: mesoporous silica nanoparticles, amorphous silica, silica-based materials, nanofibers and silica hybrids, and the main biomaterials developed are scaffolds, grafts, aerogels, hydrogels, membranes and drug delivery systems.
10 Jun 2022Submitted to Biotechnology and Bioengineering
10 Jun 2022Assigned to Editor
10 Jun 2022Submission Checks Completed
04 Jul 2022Reviewer(s) Assigned
10 Mar 2023Review(s) Completed, Editorial Evaluation Pending
10 Mar 2023Editorial Decision: Revise Major