Case Discussion
Classical or true EM is precipitated by trigger factors such as
infective agents like the herpes simplex virus, Mycoplasma pneumoniae,
drugs like anticonvulsants, antibiotics, and non-steroid
anti-inflammatory drugs, any underlying malignancy, or connective tissue
disorders, and is not associated with any specific serological
abnormalities. EM cases associated with LE lesions where an EM trigger
factor is missing are considered an RS diagnostic criterion.