Table-14. Tox21 Pathway Parameters for the ligands
† Eritadenine (ERA), Ergosterol Peroxide (ERPO),
Gallic Acid (GA), Pleuran (PLEU).
‡ Androgen Receptor (NR-AR), Androgen Receptor Ligand
Binding Domain (NR- AR- ABD), Antioxidant Response Element (SR-ARE),
Aryl Hydrogen Receptor (NR- AhR), Aromatase enzyme (NR-Aromatase),
ATPase family AAA domain-containing protein 5 (SR-ATAD5), Estrogen
Receptor (NR-ER), Estrogen Receptor Ligand Binding Domain (NR-ER-LBD),
Heat Shock Factor Response Element (SR-HSE), Mitochondrial Membrane
Potential (SR-MMP), Peroxisome Proliferator- Activated Receptor Gamma
(NR-PPAR-γ) and p53 binding site (SR-p53).
§ Negative or no toxicity (-), Positive or in
probability of being actively toxic (+).