Antibiotic use
Patient and antibiotic days, LOT per 1000 patient days, DOT/LOT ratios, and most commonly used antibiotics during the study period by PHO unit and by type of hospital (pediatric versus general) are shown inTable 2. Ceftazidime was commonly used in PHO units located in general hospitals, while piperacillin/tazobactam monotherapy was commonly used in the BMT unit. After intervention, ceftazidime use decreased in the two PHO units located in general hospitals (from 19% to just 1.1%) and remained low in units located in pediatric hospitals throughout the surveillance period (0.2% before and 0.4% after intervention). Regarding the use of glycopeptides, their use remained high and essentially unchanged after intervention. More specifically, their use was 30.4%, both prior to and after the intervention in PHO units located in general hospitals, and slightly increased after the intervention from 24.9% to 27.2% in PHO units located in pediatric hospitals.