PHIG intervention
The surveillance of antibiotic use and the educational intervention
about the implementation of the CPG started in December 2017 for five of
the units; one started in March 2018 due to local resource restrictions,
while one of the units participated in data collection only during the
pre-intervention period (June 2016 to December 2017) due to limited
resources. The same demographic and clinical data were recorded in the
post-intervention two-year period (January 2018 to December 2019), to
compare antimicrobial use before and after implementation of the
guidelines for the management of FN in children with cancer and HSCT
recipients.13