Results
In our study PT, aPTT, D-dimer, INR, PLT levels of a total of 238 individuals who were admitted to our hospital with a suspicion of COVID-19 were examined and evaluated according to their COVID-19 results. Half of these 238 individuals were individuals with a negative COVID-19 test result and the other half were patients with a positive COVID19 test result. The descriptive information of the study is given in table 1.
The test reference range of the samples analysed in Biochemistry Laboratory was taken as 10-14 seconds (sec) for prothrombin time (PT). While 11.46±0.86 sec. PT mean value was found in PCR negative individuals, 12.97±3.65 sec was found in PCR positive patients. When PT values were examined, a significant difference was found between both groups and the difference was found as statistically significant (p<0.001), (Table 2).
The test reference range of the samples analysed in Biochemistry Laboratory was taken as 18-36 seconds (sec) for activated partial thromboplastin (aPTT). While 24.38±3.40 sec. aPTT mean value was found in PCR negative individuals, 24.18±4.83 sec was found in PCR positive patients. No significant difference was found between the two groups (Table 2).The test reference range of the samples analysed in Biochemistry Laboratory was taken as 0-0.5 µg/ml for D-dimer. While 0.23±0.12 µg/ml D-dimer mean value was found in PCR negative individuals, 2.10±5.60 µg/ml was found in PCR positive patients. When D-dimer values were examined, a significant difference was found between both groups and the difference was found as statistically significant (p<0.001), (Table 2).The test reference range of the samples analysed in Biochemistry Laboratory was taken as 0.8-1.2 for International Normalized Ratio (INR). While 0.99±0.12 INR mean value was found in PCR negative individuals, 1.14±0.35 was found in PCR positive patients. When INR values were examined, a significant difference was found between both groups and the difference was found as statistically significant (p<0.001), (Table 2).The test reference range of the samples analysed in Biochemistry Laboratory was taken as 142-424*109/L for platelet (PLT). While 266.75±71.36*109/L PLT mean value was found in PCR negative individuals, 241.18±96.64*109/L was found in PCR positive patients. When PLT values were examined, a significant difference was found between both groups and the difference was found as statistically significant (p=0.002), (Table 2). In addition, the evaluation by gender for all parameters is given in table 2.