Procedures
To assess the relationship between nocturnal enuresis and
hyperfiltration, we retrospectively evaluated children with SCD enrolled
in the Evaluation of Nocturnal Enuresis and Barriers to Treatment among
Pediatric Patients with SCD study (PEESC; NCT01959958) and prospectively
identified children who reported nocturnal enuresis and were enrolled in
the longitudinal cohort study Sickle Cell Clinical Research and
Intervention Program (SCCRIP, NCT02098863).