Statistical analysis
Results were expressed as medians with their interquartile ranges (IQR)
and frequency (%) for continuous and categorical variables,
respectively. Assessment of differences between inpatients and
outpatients was performed using Chi-squared test, or Fisher’s exact test
for categorical variables, and Mann-Whitney U test for continuous
variables.
In addition, selected variables from the demographic, clinical
presentation, inflammatory markers, and all significant immune-subsets
were subjected to a univariable logistic regression with the composite
outcome of ICU admission and mortality in the first 30 days. Variables
significant in the univariable analyses (p <0.05) were
assessed using multivariable logistic regression to determine the
independent predictors of the mentioned outcome.
An alpha threshold of 0.05 was used for statistical significance.
Statistical analysis was performed using R studio (RStudio Team (2016).
RStudio (Version 1.1.456): Integrated Development for R. RStudio, Inc.,
Boston, MA URL).