Positivity threshold TOSS ≥ 5
Expo 1
Expo 2
Expo 3
Expo 4
Expo 5
Expo 6
TOSS Scoring units
5.7 ± 0.8
5.5 ± 0.6
5.8 ± 1.2
5.7 ± 1.1
6.8 ± 1.5
6.3 ± 1.9
TOSS Scoring Units [Min; Max]
[0; 7]
[0; 7]
[0; 8]
[0; 8]
[0; 9]
[0; 9]
Time until positivity, min
68.3 ± 25.6
91.4 ± 62.03*
77.1 ± 34.9
82.8 ± 31.4 *
72.8 ± 28.1
65.7 ± 21.4
Cumulative dose of birch allergen exposure, ng 0.06 ± 0.02 0.08 ± 0.06** 0.07 ± 0.03 0.08 ± 0.03** 0.07 ± 0.03 0.06 ± 0.02