Positivity threshold TOSS ≥ 5 CAC N=16 EEC Day 1 N=8 † EEC Day 2 N=12 ‡
TOSS units
6.2 ± 1.1
5.7 ± 0.8 n.s. 5.5 ± 0.6 n.s.
TOSS [Min; Max] [0; 9] [0; 7] [0; 7]
Time until positivity, min
35 ± 15.06
81.2 ± 33.9 p<0.05 101.6 ± 57.3 p<0.05
Cumulative dose of birch allergen exposure, ng
980 ± 784.5
0.07 ± 0.03 p<0.001 0.07 ± 0.07 p<0.001