Study design and participants
This retrospective cohort study reports reproductive intentions and outcomes of women who underwent fertility-sparing surgery or fertility preservation procedures for invasive cervical cancer in a tertiary referral clinic for gynecological oncology in the Netherlands. Using a computerized database, patients ≤ 45 years old, diagnosed with invasive cervical cancer stage IA2 to IVA and who desired to maintain reproductive potential between January 2009 and January 2020 were identified. Patient, tumor and treatment data were retrieved from medical files. Data on reproductive intentions and pregnancy outcomes were derived from both medical files and postal questionnaires sent to all but deceased patients.