Fig. 2. The basic information of the COVID-19 cohort. (A) The severity percentage of asymptomatic, presymptomatic, and symptomatic patients with COVID-19. Blue represents non-severe (mild or moderate), and red represents severe or critical. (B) The basic disease rate of patients with COVID-19. The vertical axis represents the percentage of basic diseases (%). The horizontal axis represents the number of basic diseases one patient has. (C) A comparison of the ICU rate between patients with presymptomatic and symptomatic severe COVID-19. The vertical axis indicates the rate of ICU. ’Pre-sym & S’ and ’Sym & S’ represent the severe presymptomatic and symptomatic patient group, respectively. (D) The highest six-category scale scores in severe COVID-19 patients. The vertical axis indicates the number of highest six-category scale scores (%). Scores represent their severity, including 1-discharged, 2-hospitalization without requiring oxygen therapy, 3-hospitalized with low-flow oxygen therapy, 4-hospitalized with non-invasive ventilation and/or high-flow oxygen therapy, 5-hospitalized for ECMO and/or mechanical ventilation, and 6-death. (E) and (F) The boxplot reflects the viral load (CT value) and SARS-COV-2 antibody IgG and IgM levels in three groups as a function of hospital stay. *** represents P -value < 0.001. ** representsP -value < 0.01. * represents P -value < 0.05. NS. represents P -value > 0.05. The three colors of red, orange and blue represent the asymptomatic, presymptomatic, and symptomatic group, respectively.