Supplementary Figure 9
(A-B ). Scatter dot plots of the proportions of
CD4+ (A ) and CD8+(B ) T cells expressing different surface and intracellular
markers in adult blood (AB) versus cord blood (CB).
(C-D). Scatter dot plots of the proportions of
CD4+ (C ) and CD8+(D ) T cells expressing IFN-γ, IL-4, IL-5, IL-10, and IL-13 in
adult blood (AB) versus cord blood (CB).
(E-F ). Clustering results retrieved by Spectre for
CD8+ T cells based on the combined AB and CB
experiment. E. Uniform manifold approximation and projection
(UMAP) plot visualizing clustering results from Spectre. F. Dot
plot visualizing the clusters identified by Spectre and their marker
expression profiles. The size of the dot corresponds to the percentage
of cells expressing the corresponding markers and the color gradient
reflects the average normalized expression of the corresponding markers.
N=5 per group and data are presented as mean ± s.e.m., with *
p<0.05 and ** p<0.01 by unpaired Mann-Whitney U
test.