miRNAs differential expression
E. multiloculari s infection can cause liver damage in mice, but the mechanism of damage is still unclear. This study mainly explores the mechanism of liver injury from the regulation of miRNAs. The mouse liver tissue close to the lesion site was isolated for transcriptome sequencing. A total of 71 differentially expressed miRNAs were screened out(Fig3B-D, Table S1), and deleted of non-mouse miRNAs, there are 36 miRNAs among them with a large difference of |FC|>0.585(Table3), and these miRNAs may be related to liver damage caused by E. multiloculari s.