A metal-free, green, and sustainable functionalization of unactivated
alkyl sp3 C–H bonds is reported using iodine (III) as
a feasible dehydrogenation agent under visible light or KBr, and alkyl
chlorides, bromides, alcohols, and ketones could be constructed by
addition of different
coupling reagents. Cheap and safe
iodobenzene diacetate was used to form a strong radical to activate the
alkyl sp3 C–H bond in a highly efficient manner,
which can construct different
alkylation products by adding corresponding coupling reagents.
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