entry
reagent (equiv) DIB (equiv) H2O (mL) Solvent (2.5 mL) Time (h) Yieldb (%)
1 NaCl (1) 1 0.5 DCM 3 4a (32)
2 NaCl (1) 2 0.5 DCM 3 4a (35)
3 NaCl (1) 3 0.5 DCM 3 4a (36)
4 NaCl (1) 3.5 0.5 DCM 3 4a (38)
5 NaCl (1) 4 0.5 DCM 3 4a (39)
6 NaCl (1.5) 3.5 0.5 DCM 3 4a (41)
7 NaCl (1.5) 3.5 - DCM 3 4a (0)
8 NaCl (3) 3.5 0.1 DCM 3 4a (51)
9 NaCl (3) 3.5 0.3 DCM 3 4a (57)
10 NaCl (3) 3.5 0.5 DCM 3 4a (62)
11 NaCl (3) 3.5 0.7 DCM 3 4a (61)
12 NaCl (3) 3.5 1 DCM 3 4a (56)
13 NaCl (3) 3.5 0.5 DMSO 3 4a (0)
14 NaCl (3) 3.5 0.5 DMF 3 4a (0)
15 NaCl (3) 3.5 0.5 EtOH 3 4a (14)
16 NaCl (3) 3.5 0.5 DCM 1 4a (54)
17 NaCl (3) 3.5 0.5 DCM 2 4a (59)
18 NaCl (3) 3.5 0.5 DCM 3 4a (62)
19 NaCl (3) 3.5 0.5 DCM 4 4a (70)
20 NaCl (3) 3.5 0.5 DCM 5 4a (80)
21 NaCl (3) 3.5 0.5 DCM 6 4a (79)
22 KCl (1.5) 3.5 0.5 DCM 5 4a (26)
23 CuCl2(1.5) 3.5 0.5 DCM 5 4a (0)
24c NaCl (1.5) 3.5 0.5 DCM 5 4a (32)
25d NaCl (1.5) 3.5 0.5 DCM 5 4a (0)
26 KBr(1.3) 3.5 0.5 DCM 5 4b (64)
27e - 1 0.5 DCM 14 4c (69)