REFERENCES:
  1. Shin YH, Hwang J, Kwon R, et al. Global, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019. Allergy . 2023;78(8):2232-2254. doi:10.1111/all.15807
  2. Liu AH. Revisiting the hygiene hypothesis for allergy and asthma. J Allergy Clin Immunol . 2015;136(4):860-865. doi:10.1016/j.jaci.2015.08.012
  3. Akdis CA. Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions? Nat Rev Immunol. 2021 Nov;21(11):739-751. doi: 10.1038/s41577-021-00538-7. Epub 2021 Apr 12. PMID: 33846604.
  4. Hurley S, Franklin R, McCallion N, et al. Atopic outcomes at 2 years in the CORAL cohort, born in COVID-19 lockdown. Pediatr Allergy Immunol . 2023;34(9):e14013. doi:10.1111/pai.14013
  5. O’Donovan SM, Murray DM, Hourihane JO, Kenny LC, Irvine AD, Kiely M. Cohort profile: The Cork BASELINE Birth Cohort Study: Babies after SCOPE: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints. Int. J. Epidemiol. 2015; 44 (3): 764-775. 10.1093/ije/dyu157
  6. Illi S, von Mutius E, Lau S, et al. The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol . 2004;113(5):925-931. doi:10.1016/j.jaci.2004.01.778
  7. Hurley S, Franklin R, McCallion N, et al. Allergy-related outcomes at 12 months in the CORAL birth cohort of Irish children born during the first COVID 19 lockdown. Pediatr Allergy Immunol . 2022;33(3):e13766. doi:10.1111/pai.13766
  8. de Silva D, Halken S, Singh C, et al. Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials. Pediatr Allergy Immunol . 2020;31(7):813-826. doi:10.1111/pai.13273
  9. Yucel E, Suleyman A, Hizli Demirkale Z, Guler N, Tamay ZU, Ozdemir C. ’Stay at home’: Is it good or not for house dust mite sensitized children with respiratory allergies?. Pediatr Allergy Immunol . 2021;32(5):963-970. doi:10.1111/pai.13477
  10. Munblit D, Greenhawt M, Brough HA, et al. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics. Pediatr Allergy Immunol . 2022;33(10):e13851. doi:10.1111/pai.13851