Figure 1: PFD and BIBF ameliorated impaired lung function in silica-treated mice. (A) Schematic diagram of intragastric administration of PFD or BIBF in silica-induced pulmonary fibrosis mice (n=9 per group). Indexes of lung capacity, including IC (B) , and FVC (C) . Indexes of flow rate, including FEV100(D) and MMEF (E) . Indexes of resistance, including RI(F) . Indexes of lung compliance, including Cdyn (G)and Cchord (H) . Bar values were shown as the mean ± SE. ∗ denotes the group compared to Si group. ∗P < 0.05, and ns indicates no significance. The range of P -values for ∗ and # is identical.