Abbreviations
ECM, extracellular matrix
IPF, idiopathic pulmonary fibrosis
PFD, pirfenidone
BIBF, nintedanib
FGFR, fibroblast growth factor receptor
VEFGR, vascular endothelial growth factor receptor
PDGFR, platelet-derived growth factor receptor
PBS, sterile phosphate buffer
CMC-Na, sodium carboxymethylcellulose
TBST, Tris-buffered saline with Tween-20
IC, inspiratory capacity
FVC, forced vital capacity
FEV100, forced expiratory volume in 100 ms
RI, airway resistance
Cdyn, dynamic compliance
Cchord, chord compliance
MMEF, mean mid-expiratory flow
BALF, bronchoalveolar lavage fluid
HE, Hematoxylin and Eosin
HYP, hydroxyproline
cDNA, complementary DNA
RIPA, Radio Immunoprecipitation Assay
PVDF, polyvinylidene fluoride
ELISA, enzyme-linked immunosorbent assay
RNA-seq, RNA sequencing
DEGs, differentially expressed genes
KEGG, Kyoto Encyclopedia of Genes and Genomes
SEM, standard error of the mean
ESI, electrospray ionization
APCI, atmospheric pressure chemical ionization
ANOVA, analysis of variance