Statistical analysis
All statistical analyses were performed in R version 3.5.3. Before the
analysis, all the data were tested for normal distribution and variance
homogeneity. For data that adhere to normal distribution and variance
homogeneity, analysis of variance (ANOVA) is employed. Alternatively,
Kruskal-Wallis H Test was used for data with abnormal distribution or
uneven variance. For all graphs, data were expressed as mean ± SEM
(standard error of the mean), and P -values < 0.05 were
considered statistically significant.