Time to Successful Anesthesia Induction:
Our comprehensive analysis, drawing data from five out of six studies,
[13-17] highlighted a significant advantage of propofol. The time
required for a successful anesthesia induction was significantly shorter
with propofol compared to ciprofol, with a mean difference of 0.08
minutes (95% CI: 0.00 to 0.15, p = 0.04, I2 = 77%). Subgroup analyses
however showed us that there was a statistically significant difference
with 0.5 mg resulting in a shorter time to induction for propofol and no
difference in the 0.4 mg group. Interestingly, a leave-one-out
sensitivity analysis highlighted the study ”Wang X 2022” as a source of
substantial heterogeneity within the subgroup receiving 0.4 mg of
treatment. Upon its removal, subgroup-specific heterogeneity
significantly decreased to 0%, and overall heterogeneity saw a minor
reduction to 73%.