Results
There were 33 participants in whom both markers were measured. We found that HE4 elevated above 150 pmol/l was present in all 9 cases of ovarian cancer and in the single case of pancreatic cancer. Other conditions associated with elevated HE4 included hepatic cirrhosis. Normal HE4 levels below 77pmol/l seen in 16 cases were associated with non-malignant gynaecological conditions and with no identified cause for elevated CA125 (See Table). Two cases with HE4 between 77 and 149 pmol/l had no gynaecological conditions and 2 with values in this range had elevated CA125 on 2 occasions without an identifiable cause.