Conclusion
This study aims to find potential genetic factors that may be associated
with severe outcomes of COVID-19; It was conducted on individuals with a
history of COVID-19 in the Iranian population. The present study shows
that the rs759499720/ACE2, rs776459296/ACE2, rs386818798/TMPRSS2,
rs771922681/TYK2, rs753470142/TYK2, c.675G>T/TYK2,
rs147760034/SLC6A20, rs139008024/SLC6A20 and rs759744926/IFNAR2 variants
are genetic risk factors for severe forms of COVID-19. However, further
research with a larger sample size and different human populations is
needed to confirm the findings of this study. Also, more studies are
necessary to find the association between these found variants and
gender and different ethnicities.