Introduction
Since its inception in 2019, coronavirus disease 2019 (COVID-19) rapidly
became a pandemic affecting almost all the countries of the world. Prior
studies including ours1 showed the effect of COVID-19
in hematopoietic cells causing lymphopenia, leukocytosis, neutrophilia,
thrombocytopenia and leukoerythroblastosis. However, effect of COVID-19
and hematologic malignancies has not been reported widely. In this
article, we are presenting two unique cases of B-lymphoblastic leukemia
(B-ALL) in pediatric patients with a previous history of COVID-19
infection. Both the cases had complete resolution of COVID-19 infection
during the time of presentation with acute leukemia.