2.3. Inclusion and Exclusion Criteria
The inclusion criteria were age range between 18 and 90 years, being
hospitalized, patients with COVID-19, not being hospitalized in the
intensive care unit at the time of entrance to the study, patients
without coagulopathy, patients without a history of stroke, ocular and
cerebral hemorrhage, women those were not pregnant or breastfeeding,
patients without cancer, porphyria, liver and renal dysfunction, having
no massive surgery in the past two weeks, history of intolerance or
allergy to PTX or any type of Xanthine.
Exclusion criteria were the occurrence of any bleeding or severe side
effects during the study such as gastrointestinal intolerance that does
not respond to predetermined measures of antidote use, skin drug
reactions, heart attack and stroke during the study, unstable vital
signs, being intubated under mechanical ventilation, hospitalization in
ICU, and patients under the treatment with any therapeutic blood
thinner.