Demography and hematological parameters
We evaluated 19 patients of cirrhotic liver disease, 36 normal health care workers and 10 unvaccinated healthy individuals at one year duration after initial dose of vaccination. All individuals received two doses of ChAdOx1nCoV-19 vaccine. The demographic and laboratory findings of study population are described in Table I. The median age of cirrhotic patients was 55 (44-67) years with male female ratio of 2.8:1. Underlying causes of cirrhosis were Hepatitis C virus (52.63%), alcoholic hepatitis (15.78%), hepatitis B virus (10.52%), cryptogenic/ nonalcoholic steatohepatitis (10.52%) and other (10.52%) respectively. Of 19 patients, 84.21 % had compensated and 15.78% had non-compensated cirrhosis with 78.94% patients belonging to Child–Turcotte–Pugh (CTP) class A (15; 78.94%) and B (4; 21.05%) cirrhosis.