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\begin{document}

\title{Study on Anatomical Variations of Nose and Paranasal sinuses in patients
with sinonasal polyposis}



\author[1]{Akriti Shrestha}%
\author[2]{Sabi Rana}%
\author[3]{Sagar Devkota}%
\author[1]{Kolaj Kattel}%
\author[1]{Astika Shrestha}%
\affil[1]{Nobel Medical College Teaching Hospital P Ltd}%
\affil[2]{Kathmandu Medical College and Teaching Hospital}%
\affil[3]{Kulhudhuffushi Regional Hospital}%


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  \date{June 18, 2024}


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\begin{abstract}
Background Sinonasal anatomical variations are common and its knowledge
plays an integral part in the management of sinonasal disease. Although
sinonasal anatomic variations have been postulated as a risk factor for
sinus disease, its role in the pathogenesis of nasal polyp is still
unclear. This study was done to determine the prevalence of sinonasal
anatomical variations by CT imaging and examine its association with
sinonasal polyposis. Methodology A descriptive cross sectional study was
conducted from January, 2019 to January, 2020 at a tertiary care center
in Nepal after receiving ethical approval from the Institutional Review
Committee of the hospital. Patients above 17 years of age having
sinonasal polyp and not responding to 3-4 weeks of medical treatment
were included in the study. Convenience sampling was done. Data were
collected and entered in Microsoft Excel and analyzed using Statistical
Package for the Social Sciences version 24.0. Results Among 72 patients,
the prevalence of anatomical variations of nose and paranasal sinuses
was found to be in 62 patients (86.11\%). Agger nasi (79.09\%) and
deviated nasal septum (72.5\%) were the common variations noted. Single
variation was found in 29\% and multiple variations in 70.9\% Conclusion
Our study showed that the prevalence of sinonasal anatomical variations
was higher in patients with sinonasal polyp and the severity of polyp
increases with the presence of more than one variation in a patient. Key
words Computed tomography scan, sinonasal anatomical variations,
sinonasal polyp%
\end{abstract}%



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