3.3. Effect of DMF on Micronucleus (MN) appearance
Table 2 showed no significant difference in the appearance of
micronucleated polychromatic erythrocytes (Mn-PCEs%) in Group II rats
compared to the control group.
Furthermore, table 2 also showed that acute exposure to DOX (90mg/kg)
(Group III ) caused a significant increase(P <0.05) in the frequency of MN appearance in
comparison to such appearance in control (Group I ). in
contrast, DMF pretreatment prior to DOX Exposure (Group IV )
caused a significant decrease (P <0.05) in the
appearance of Mn-PCEs when compared to Group III .