This case report highlights the potential benefits of aDBS in PD patients with motor complications. The use of a feedback algorithm based on beta-band activity recorded from the STN electrodes allows for real-time adjustments to stimulation parameters, resulting in improved motor function and reduced side effects. The patient in this case experienced significant improvement in motor function and quality of life during the trial period. However, larger studies are needed to confirm the efficacy of aDBS in PD patients.
Fianlly, Adaptive DBS is a promising approach to the treatment of PD patients with motor complications. This case report highlights the potential benefits of aDBS in improving motor function and reducing side effects in PD patients. Further studies are needed to confirm the efficacy of aDBS in larger patient populations.
References:
1. Little, S., Pogosyan, A., Neal, S., Zavala, B., Zrinzo, L., Hariz, M., ... & Brown, P. (2013). Adaptive deep brain stimulation in advanced Parkinson disease. Annals of neurology, 74(3), 449-457.