Results
Compared to expected rates in the general population, CCS had lower rates of seropositivity for measles (20/26, 77%), mumps (12/18, 66%), rubella (16/21, 76.2%), varicella (10/23, 43.4%), tetanus (10/20, 50%), and hepatitis B (6/18, 33%). CCS with hematological malignancies had the lower rates of seropositivity with protective antibodies in only 70% (14/20) of measles, 61.5% (8/13) of mumps, 75% (12/16) of rubella, 31.25% (5/16) of varicella , 40% (6/15) of tetanus, and 23% (3/13) of hepatitis B titers. In both subgroups all values, except for mumps, were significantly lower than literature rates of expected antibody retention. Table 1 has a summary of seronegativity rates and statistical analysis.
Table : Seronegativity of the general population compared to CCS with all malignancies and CCS with hematological malignancies.