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\begin{document}

\title{Delirium in hospitalized elderly patients with non-severe SARS-CoV-2
infection: an observational clinical study}



\author[1]{Guanghui An}%
\author[1]{Zhihua Mi}%
\author[1]{Dandan Ou}%
\author[1]{Xiaoxiao Cao}%
\author[2]{Tinan Feng}%
\author[1]{Qidong Liu}%
\author[1]{Lize Xiong}%
\author[1]{Cheng Li}%
\affil[1]{Shanghai Fourth People's Hospital}%
\affil[2]{Affiliation not available}%


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  \date{May 22, 2024}


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\begin{abstract}
\textbf{Objective} Delirium has been reported in all the course of
COVID-19, especially in aged patient with severe SARS-CoV-2 infection,
but there are few studies on these millions of patients with none-severe
omicron infection. To study the incidence of delirium and its factors in
hospitalized elderly patients with non-severe Omicron infection,we
reported this single-center observational study.~\textbf{Methods}
Patients tested positive for SARS-CoV-2 infection at the hospital were
included. We used the 3-min diagnostic Confusion Assessment Method for
delirium diagnosis. We collected the demographic data, medical history,
number of vaccine doses against COVID-19, the first laboratory tests and
chest computed tomogram, days to the outcome, and medications to treat
COVID-19.~\textbf{Results} The data of 311 (131M,180F, aged75\selectlanguage{ngerman}±7y)
patients were analyzed, of whom 73 ( 29M,44F,~ 23.47\%) patients were
diagnosed with delirium. Higher incidence was associated with lager age,
lager body mass index, smaller total protein, lower albumin-to-globulin
ratio, and higher platelet-large cell ratio. These parameters were used
to create a risk prediction model, which showed good predictive
accuracy. ~\textbf{Conclusion}~We found that delirium is frequently seen
in elderly patients even with non-severe Omicron infection. Age, body
mass index, total protein, albumin-to-globulin ratio, and platelet-large
cell ratio were identified as independent factors for delirium. Our
findings may be useful to physicians in early prevention and treatment
of delirium. ~%
\end{abstract}\selectlanguage{ngerman}%



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