Title: Mononeuropathy Multiplex as An Uncommon Presentation of
Intravascular Lymphoma: A Case Report
Bahram Haqi-Ashtiani 1, Parichehr Moghaddam2, Farzaneh Barzkar 3, Ali Zare
Mehrjerdi4, Mostafa Almasi-Dooghaee 5
*
1 MD, Assistant professor, Firoozgar
hospital, Department of Neurology, School of Medicine, Iran University
of Medical Sciences, Tehran, Iran; Email:
bhaghi2000@yahoo.com
2 MD, Firoozgar hospital, Department of
Neurology, School of Medicine, Iran University of Medical Sciences,
Tehran, Iran. Email:
parichehr.moghaddam@gmail.com
3 MD, Center for Educational Research in
Medical Sciences(CERMS), School of Medicine, Iran University of Medical
Sciences, Tehran, Iran. Email:
barzkarfarzane@gmail.com
4 MD, Associate Professor of Pathology,
Firoozgar Clinical Research Development Center (FCRDC), Department of
Pathology, Iran University of Medical Sciences, Tehran, Iran. Email:
azaremehrjardi@yahoo.com
5 MD, Assistant professor, Firoozgar
hospital, Department of Neurology, School of Medicine, Iran University
of Medical Sciences, Tehran, Iran; Email:
a_mostafa108@yahoo.com
* Corresponding author: Mostafa Almasi-Dooghaee
Address: Neurology department, Firoozgar hospital, Valadi St., Valiasr
Ave., Tehran, Iran
email:
a_mostafa108@yahoo.com
Tel: +98 21 82141817
List of abbreviations:
MM: Multiple Mononeuropathy
ONLS: Overall neuropathy limitations scale
IVLBCL: Intravascular large B-cell lymphoma
IVL: Intravascular lymphoma
Abstract:
Case Presentation: A 64-year-old man presented with asymmetric
paresthesia and subsequent weakness of his feet and a 10-kg weight loss
over 40 days. Electrodiagnostic studies revealed distal axonal
sensory-motor polyneuropathy with ongoing axonal loss. A peroneal nerve
biopsy showed intravascular proliferation of CD-20 positive lymphocytes,
which suggested intravascular large B-cell lymphoma.
Clinical Message: Although intravascular lymphoma rarely
presents with peripheral neuropathy, learning about this presentation
can lead to timely diagnosis and improved prognosis in patients with
intravascular lymphoma.