Conclusion
Though no topical therapies have been studied to specifically reduce the
viral load and potential aerosolization of SARS-CoV-2 during upper
airway mucosal surgery, Povidone – Iodine solutions have demonstrated
effective virucidal activity against related coronaviruses in numerous
studies. They are relatively safe to use in the upper airway, require
very brief application times, and may potentially reduce the risk of
SARS-CoV-2 aerosolization and transmission during upper airway mucosal
surgery.