2.9. Analysis of Kd and IC50 value of monoclonal antibodies against SARS-CoV-2 spike variants
The Kd values of the 74 monoclonal antibodies which are available publicly in research articles were collected and was tabulated against the wildtype as well spike variants. Similarly, the IC50values were also tabulated from the available in vitro studies from different research articles and was compared with that of wild type or other SARS-CoV-2 spike variants. The variations in the Kd value as well as IC50 was denoted with red color which denotes the reduction in binding affinity as well as the efficacy of antibody neutralization.