Characteristicsa N = 34 b
Age (years)b
43 ± 13 (24-68)
Gender, malec
31 (91%)
Height (cm)b
160 ± 7 (146-179)
Weight (kg)b
84 ± 17 (54-134)
BMI (kg/m2)b,d
32.5 ± 5.5 (21.6-47.0)
Normalc
1 (2.9%)
Overweightc,d
4 (12%)
Obesityc,
29 (85%)
Estimated CrCL (mL/min)b,e,
87 ± 31 (25-165)
15 ≤ Estimated CrCL < 30 1 (3%)
30 ≤ Estimated CrCL < 60
8 (24%)
Estimated CrCL ≥ 60
25 (74%)
Baseline serum urate (mg/dL)b
9.61 ± 1.67 (5.8-13.0)
Post-treatment serum urate (mg/dL)b
5.4 ± 1.1 (3.1 – 7)
Self-reported medications related to SU/gout c,f
Drugs that lower serum urate 10 (29%)
Losartan 1 (2.9%)
HMG-CoA inhibitors 5 (15%)
Calcium channel blockers 5 (15%)
Drugs that increase serum urate 22 (65%)
Angiotensin converting enzyme inhibitors 5 (15%)
Angiotensin receptor blockers (not losartan) 1 (2.9%)
Beta-blockers 6 (18%)
Diuretics 4 (12%)
Non-steroidal anti-inflammatory drugs 16 (47%)