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\begin{document}

\title{Viral co-infection with human respiratory syncytial virus in suspected
acute and severe respiratory tract infections during COVID-19 pandemic
in Yaound\selectlanguage{ngerman}é-Cameroon, 2020-2021\selectlanguage{english}}



\author[1]{Moïse Henri MOUMBEKET YIFOMNJOU}%
\author[1]{Gwladys Monamele}%
\author[1]{Mohammed NJANKOUO RIPA}%
\author[1]{Abdou Fatawou Modiyinji}%
\author[1]{Paul Alain NGOUPO}%
\author[2]{Onana BOYOMO}%
\author[1]{Richard NJOUOM}%
\affil[1]{Centre Pasteur du Cameroun}%
\affil[2]{University of Yaounde 1 Faculty of Sciences}%


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  \date{June 08, 2024}


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\begin{abstract}
Background: Acute lower respiratory tract infections (ALRI) are one
leading cause of morbidity and mortality among people of all ages
worldwide, particularly in low- and middle-income countries (LMICs). The
purpose of this study was to determine epidemiological characteristics
of respiratory viruses in ARI patients during the SARS-CoV-2 pandemic in
Yaound\selectlanguage{ngerman}é, Cameroon. Methods: Patients were monitored for respiratory
symptoms as part of surveillance of SARS-CoV-2 and other respiratory
viral infections. Patients of all ages with respiratory symptoms less
than 5 days were considered. Sociodemographic and clinical data as well
as nasopharyngeal samples was collected from patients. Nasopharyngeal
samples were tested for SARS-CoV-2, Influenza and Respiratory Syncytial
Virus (RSV) using real-time reverse-transcription polymerase chain
reaction methods. Virus distribution and demographic data were analyzed
with R version 2.15.1. Results: From July 2020 to October 2021, 1120
patients were included. The overall viral detection rate was 32.5\%,
including 9.5 \% for RSV (Respiratory Syncytial Virus), 12.6 \% for
influenza virus and 12.8 \% for SARS-CoV-2 (Severe Acute Respiratory
Syndrome Coronavirus 2). Co-infections were detected in 6.9\% of
positive cases. While RSV and influenza virus showed seasonal trends,
SARS-CoV-2 was detected throughout the study period. Conclusion: We
found that during SARS-CoV-2 pandemic, respiratory viruses play an
important role in aetiology of influenza-like illness in Cameroon, and
this observation was true for patients of all ages.%
\end{abstract}\selectlanguage{ngerman}%



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