Secondary endpoint
After single ablation, the recurrence rate in the CLBBB group was
significantly higher than that in the Non-CLBBB group (54.8% vs.
31.5%, HR 1.71, 95% CI 1.04-2.79, P=0.034) (Figure 2). In univariate
analysis, QRS duration, heart failure,
CHA2DS2-VASc score, and CLBBB were
associated with recurrence. In multivariate analysis, it was shown that
heart failure (HR 1.82, 95% CI 1.14-2.91, P=0.010),
CHA2DS2-VASc score (HR 1.21, 95% CI
1.03-1.43, P=0.022), and CLBBB (HR 2.19, 95% CI 1.09-4.40, P=0.031)
were independent risk factors of recurrence after catheter ablation of
AF (Table 4).
Fourteen patients (33.3%) in the CLBBB group and 37 (22.0%) patients
in the Non-CLBBB group underwent redo procedures. In redo procedures,
pulmonary vein reconnections occurred in 12 (85.7%) patients with CLBBB
and 30 (81.0%) patients without CLBBB (P=0.121). After the last
procedure, the recurrence rate was significantly higher in the CLBBB
group than the Non-CLBBB group (35.7% vs. 16.1% P=0.004).