2.8 Data statistical analysis
All data in this study were expressed as mean ± standard deviation (SD).
Data analysis was performed by GraphPad Prism 8.0. The heatmap was
generated using the pheatmap package (R version 4.0.1). The pathway
enrichment was performed using the MetaboAnalyst
(https://www.metaboanalyst.ca/).
Significant analysis was performed by GraphPad Prism 8.0, with p
< 0.05, p < 0.01 and p < 0.001 indicated
that there were significant (*), highly significant (**) and extremely
significant (***) difference between the groups, respectively.