3.3.2. Comparison of RDV-treated patients in both waves
The RDV-treated group during Delta and Omicron waves had comparable
mortality and did not differ in the age of deceased patients, but the
former required mechanical ventilation more often (Table 4).
The mortality rate of patients treated with RDV with baseline saturation
≤95% analyzed by age showed no difference between the two pandemic
waves, while the need for mechanical ventilation was significantly more
frequent in the Delta period, both overall and in the group of patients
older than 60 years (Table 5).
Table 5. Twenty-eight days mortality and the need for
mechanical ventilation in patients treated with remdesivir during
periods of Delta and Omicron variant dominance analyzed in all patients,
only those with oxygen saturation ≤95%, including administration of
Remdesivir within 5 days of symptom onset as well as aged over 60 or 80
years.