Abbreviations: AVT, antiviral therapy; ALT, alanine aminotransferase;
ARDS, acute respiratory distress syndrome; CRP, C-reactive protein;
IL-6, interleukin-6; PCT, procalcitonin; RDV, remdesivir; SD, standard
deviation; SpO2, saturation of peripheral oxygen; WBC,
white blood cells.
Despite the lack of differences in baseline demographic and clinical
characteristics in both waves of the pandemic, patients treated with RDV
during the Delta predominance period presented significantly lower mean
white blood cell, neutrophil, and platelet counts and D-dimer
concentrations, while during the Omicron predominance period, lower
platelets and IL-6 levels compared to those not receiving antiviral
treatment (Table 2).