Abbreviations: AVT, antiviral therapy; RDV, remdesivir; SD, standard
deviation.
The population of patients treated with RDV in the Omicron wave
significantly more often required oxygen therapy during hospitalization
compared to patients who did not receive antiviral therapy (p=0.01), the
opposite was true in the Delta wave, but the difference was not
statistically significant (Table 4). There were also no significant
differences in the need for mechanical ventilation, although in both
waves, the percentage of patients requiring this management was lower
among patients treated with RDV.
In both COVID-19 waves analyzed, the mortality rate of RDV-treated
patients was significantly lower compared to patients who did not
receive the antiviral drug, with a difference of more than 2-fold in the
Delta wave and 1.5-fold in the Omicron wave.