3.3.2. Comparison of RDV-treated patients in both waves
The RDV-treated group during Delta and Omicron waves had comparable mortality and did not differ in the age of deceased patients, but the former required mechanical ventilation more often (Table 4).
The mortality rate of patients treated with RDV with baseline saturation ≤95% analyzed by age showed no difference between the two pandemic waves, while the need for mechanical ventilation was significantly more frequent in the Delta period, both overall and in the group of patients older than 60 years (Table 5).
Table 5. Twenty-eight days mortality and the need for mechanical ventilation in patients treated with remdesivir during periods of Delta and Omicron variant dominance analyzed in all patients, only those with oxygen saturation ≤95%, including administration of Remdesivir within 5 days of symptom onset as well as aged over 60 or 80 years.