Abbreviations: AVT, antiviral therapy; RDV, remdesivir; SD, standard deviation.
The population of patients treated with RDV in the Omicron wave significantly more often required oxygen therapy during hospitalization compared to patients who did not receive antiviral therapy (p=0.01), the opposite was true in the Delta wave, but the difference was not statistically significant (Table 4). There were also no significant differences in the need for mechanical ventilation, although in both waves, the percentage of patients requiring this management was lower among patients treated with RDV.
In both COVID-19 waves analyzed, the mortality rate of RDV-treated patients was significantly lower compared to patients who did not receive the antiviral drug, with a difference of more than 2-fold in the Delta wave and 1.5-fold in the Omicron wave.