Abbreviations: SpO2, saturation of peripheral oxygen.
This RDV-treated population also showed that drug administration within the first 5 days of symptom onset was associated with a significantly lower need for oxygen therapy in both waves compared to later initiation of treatment, while there was no effect of the timing of drug administration on the need for mechanical ventilation and mortality (Table 6).
Table 6. Endpoints considering the time of RDV treatment initiation - within 5 days of symptom onset versus more than 5 days.