4.0 CONCLUSION:
In conclusion, we reported for the
first time, Geranyl benzoate a phytochemical compound identified from
leaf extracts of SM. D-Limonene, p-Cymene, Thymol and
L-.alpha-Terpineol, were identified as anti-viral compounds from leaf
extracts of SM. A phytochemical constituent of Geraniin:
1,2-Benzenedicarboxylic acid, butyl 2-methylpropyl ester (1,2BAB-2-MPE)
has also been reported to have anti-viral activities. The in silico
investigation of anti-viral phytochemicals showed that 1,2BAB-2-MPE is a
potential anti-filoviral therapeutic candidate against MARV VP35.
Further investigations are needed to validate the anti-filoviral
therapeutic candidate of 1,2BAB-2-MPE and as a natural supplement or
useful for drug formulation in the fight against Marburg viruses.
Nevertheless, more research attempts are craved to isolate,
characterize, and assess other phytochemicals from S. mombin Linn leaf
extracts to justify their various pharmacological relevance.