Introduction
Functional tricuspid regurgitation(FTR) is the result of geometric
changes in valve structure in the absence of valve structural
lesions[1]. By far, FTR is most commonly
associated with pulmonary hypertension(PH) or left heart disease,
primarily due to right ventricular remodeling, resulting in lobular
tethering and tricuspid valve annulus(TA) dilation[2,
3]. There is increasing evidence that FTR is not only a marker of
concurrent cardiac disease, but also a potential driver of adverse
cardiovascular events[3]. With the in-depth study
on long-term follow-up management and prognosis of patients undergoing
mitral valve replacement(MVR), the old idea that FTR can be improved
after MVR has disappeared, and postoperative FTR can further aggravate
or cause right ventricular dysfunction(RVD)[4].
Therefore, close follow-up of patients undergoing MVR is proposed to
seek surgical intervention in FTR before severe RVD
occurs[5, 6]. However, this follow-up process
usually takes years to decades, giving clinicians ample time to
intervene with FTR to prevent or delay disease progression and thereby
improve patients’ long-term prognosis. Given the current challenges in
the management of FTR after MVR, it is important to correctly understand
the association between FTR and RVD. Always, several studies have
verified a single FTR or cumulative FTR levels associated with
postoperative RVD, but doesn’t take into account the FTR this
progressive disease throughout the postoperative changes of the
potential impact and over time, FTR level and FTR trajectory may occur
large individual differences, FTR of long-term dynamic model can more
accurately reflect the link[3]. As normal FTR
levels may go unnoticed in clinical practice and there are few studies
on the relationship between FTR longitudinal trajectory and RVD after
MVR at home and abroad. Consequently, in this research, the Group Based
Trajectory Modeling (GBTM) model was used to identify and evaluate the
trend characteristics of FTR change trajectory after MVR, so as to
explore its impact on late RV function.