FIGURE LEGENDS
FIGURE 1. Schematic representation of experimental schedule.
Flags P1 (point 1) and P2 (point 2) represent blood collection dates for
patients before (period 1) and shortly after the birch pollen season
(period 2) and in September (period 3). The birch pollen season was
determined according to pollen monitoring data.
FIGURE 2. A, Bet v 1-specific IgE levels (y-axis: kUA/L), B,
Bet v 1-specific basophil activation (y-axis: percentages of activated
basophils) in response to three different concentrations of Bet v 1
(x-axis) C, Mal d 1-specific IgE levels (y-axis: kUA/L), D, Mal d
1-specific basophil activation (y-axis: percentages of activated
basophils) in response to three different concentrations of Mal d 1
(x-axis), and E, skin sensitivity to buffer (negative control),
histamine (positive control) and apple determined at three different
time points (Figure 1) for patient 1.
FIGURE 3. A, Bet v 1-specific IgE levels (y-axis: kUA/L), B,
Bet v 1-specific basophil activation (y-axis: percentages of activated
basophils) in response to three different concentrations of Bet v 1
(x-axis) C, Mal d 1-specific IgE levels (y-axis: kUA/L), D, Mal d
1-specific basophil activation (y-axis: percentages of activated
basophils) in response to three different concentrations of Mal d 1
(x-axis), and E, skin sensitivity to buffer (negative control),
histamine (positive control) and apple determined at three different
time points (Figure 1) for patient 2.