Conclusion
We presented a one-of-a-kind case of an SLR involving only the kidney and secondary to rituximab in a 60-year-old patient after r-CHOP for mantle cell lymphoma. Clinicians should be aware of this paradoxical class effect and prolonged monitoring of renal function should be recommended during the follow-up of patients after the end of treatment with rituximab.
Early renal biopsy is indispensable for fast and adequate diagnosis, knowing that the pathology would respond well to oral corticosteroid therapy.