Inclusion Criteria:
Informed consent was signed before the trial, healthy male and female subjects aged between 18 and 45 (inclusive) at the time of signing the informed consent, of which no less than 1/3 are female subjects. Subjects have no childbirth plans and agree to take effective contraceptive measures within 6 months of the last medication, the blood pregnancy test for women of child bearing age must be negative before taking the study drug; The serum HCG test of fertile women must be negative before screening. the bodyweight of male subjects was ≥50 kg, and that of females was≥45 kg; The body mass index should range between 19–28 kg/m2, the bodyweight of male subjects was ≥50 kg, and that of females was≥45 kg; the body mass index should range between 19–24 kg/m2((inclusive); Creatinine clearance (CLCr) ≥80 mL/min, and creatinine is less than or equal to the upper limit of normal value.