3D echocardiography data
A 3D modeling of MV with AutoMVQ analysis was performed in TTE and TOE examinations of all patients enrolled in the study (figure 2). The software automatically provided results for all mitral annulus and leaflets variables. All TTE and TOE measurements and the agreement between the two methods are shown in Table 3. 3D TTE proved to be accurate in the assessment of mitral annulus and showed strong correlation with TOE. Among the TTE variables that were analyzed, tenting height, tenting area, posterior leaflet length and inter-trigonal diameter, showed the weakest correlation with TOE (Table 3), while 3D annulus area and perimeter that are most important measurements for MV, demonstrated the highest correlation (Table 3). (figure 3). Most MV components (annulus and leaflets) were found to be significantly larger in the subgroup of patients with MV pathologies either measured by TTE or TOE (Table 4).
The 3D MV area and mitral annulus perimeter were analyzed and compared in different subgroup of patients. Clinical and echocardiographic factors that affected the size of the annulus significantly were AF (p<0.001 ), LA dilatation (p<0.001 for TTE comparisons and p=0.001 for TOE comparisons) and LV dilatation (p<0.01 for all comparisons) (Table 5). Patients with CAD showed a trend but not statistically significant differences in the 3D annulus area (p=0.121 ) and perimeter (p=0.105) compared to controls.