Comparison of survivals in four different surgical approaches
The mean follow-up time of all patients was 1697 days (range 1302 to 2055 days), and the interquartile spacing between 25% and 75% was 1290 days and 2054 days, and the median follow-up time was 1639 days (4.49 years), which 5-year DFS was 89.00% (95% CI 88.21%-89.81%), and 5-year OS was 91.13% (95% CI 90.07%-92.20%). Five-year DFS of ARH was 96.88%, 5-year DFS of LRH was 81.99% (95% CI 83.21%-86.56%), 5-year DFS of RRH was 91.38% (95% CI 93.03%-94.48%), and 5-year DFS of VRH was 87.27% (95% CI 87.85%-91.47%). The total DFS curve of the four groups using Log-rank test was no significant difference (P= 0.061) (Figure 2A). However, DFS in LRH group was shorter than that in ARH group (P = 0.0294) (Figure S1A). DFS in RRH group was better than that in LRH group (P = 0.0442) (Figure S1D).
Furthermore, 5-year OS of ARH was 96.88% (95% CI 96.38%-97.37%), 5-year OS of LRH was 82.45% (95% CI 87.17%-92.00%), 5-year OS of RRH was 94.18% (95% CI 96.95%-97.23%), and 5-year OS of VRH was 91.49% (95% CI 95.42%-96.74%). The total OS curve of the four groups using Log-rank test was statistically significant (P = 0.015) (Figure 2B). Additionally, OS in LRH group was shorter than that in ARH group (P = 0.0305) (Figure S2A). OS in RRH group was better than that in LRH group (P = 0.0055) (Figure S2D). Nevertheless, the difference between other groups was not statistically significant (P > 0.05).