Study Selection and Quality Assessment
A total of 801 studies identified from the literature search were
exported into EndNote software, along with 5 additional records
identified through other sources. Duplicates were removed automatically
and manually, leaving 351 studies to screen. The selection of the
studies was performed independently by two authors (Liu. and Wang.).
Publications were evaluated dependent on predefined inclusion and
exclusion criteria.
Inclusion criteria were as follows:
(1) Randomized controlled,
prospective or retrospective observational studies; (2) Patients were
diagnosed with recurrent respiratory papillomas by histological
pathological examination; (3) Patients agreed to undergo surgical
treatment with microdebrider or CO2 laser or KTP laser;(4)
Outcomes of interest were
intraoperative and postoperative complications, and complication rates.
The following exclusion criteria were adopted: (1) Case reports,
editorials, reviews and short communications; (2) Adjuvant therapies
simultaneously;(3) Sample sizeā¤5; (4) The target outcomes is not
available. Data extraction from each included study was performed on the
basis of study characteristics and predefined outcome variables. The
following variables were retrieved from each study: year of publication,
study design, surgery modality (microdebrider or CO2 laser or KTP
laser), number of surgeries, intraoperative and postoperative
complications, complication rates. Discrepancies were resolved by
discussion. The methodological
quality assessment was performed following
the Newcastle Ottawa
Scale[23].