Short term outcomes
Outcome data with respect to mortality, reintervention and complications
post operatively are compared in Table 2 and Figure 1. A markedly lower
mortality was observed in the aortic valve resuspension cohort at all
time points during the follow up period. This difference was accounted
for by the higher operative mortality observed in the ARR cohort (1.6%
vs. 17%, p=0.003). The incidence of postoperative complications
including return to theatre, stroke, renal failure, deep sternal wound
infection and gastrointestinal bleeding was comparable in the two
cohorts.
Multivariate logistic regression analysis found both root replacement
(OR 35.2, 95% CI 2.4 – 522.0, p=0.01) and longer circulatory arrest
time (OR 1.04, 95% CI 1.01 – 1.08, p=0.01) to be significantly
associated with operative mortality (Table 3).
Data pertaining to the length of hospital stay was positively skewed. To
assess the effects of pre-operative covariates on length of stay, an
inverse gaussian generalised linear regression model was used, finding
no association between patient/operative covariates and patient stay
(p>0.05) (Table 4).