Figure 6. Allicin reduces the overproduction of inflammatory cytokines. (A) Quantitative PCR analysis of mRNA level of the IL-17A genes in back skin treated with IMQ in all groups (n=6). (B) Quantitative PCR analysis of mRNA level of the IL-17F, IL-12, IL-20, and IL-22 genes in IMQ-treated lesions with or without allicin (n=6). (C) Representative immunohistochemical images and the relative expression of IL-17A in each group (AL, allicin low-dose; AM, allicin middle-dose; AH, allicin high-dose; TAE, triamcinolone acetonide and econazole cream). Immunohistochemical staining of CD3+ cells (D), MPO+ cells (E), and F4/80+ cells (F) in IMQ-induced psoriasis-like lesions treated with or without allicin. Scale bar = 50 μm. Data are expressed as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.