LEGENDS
Figure 1. Flow chart of the whole study
Figure 2. Risk factors for osteonecrosis. Multivariate
analysis.
2A . All patients
2B. SCT patients
2C. Patients without SCT
Being over 10 years old when diagnosed with leukemia is associated with
a greater occurrence of ON, as well as suffering from relapse due to
prolonged treatment. Girls were also often affected, except in the SCT
group.
Figure 3. Evaluation of quality of life in patients with
osteonecrosis.
3A. Comparison of adult quality of life with the general
population and L.E.A cohort, according to SF-36 score
Comparing to general population, adults have a significant loss in
physical global score, social functioning (p < 0.001) and
emotional global score (p< 0.001). This negative impact is
also shown when compared with patients of L.E.A cohort, except for
mental health and emotional scores.