Contributorship statement:
Lauren Kari Dixon: Conceptualization, methodology, software, formal
analysis, writing – original draft, writing - Review & Editing
Arnaldo Dimagli: Conceptualization, methodology, software, formal
analysis, writing - Review & Editing
Ettorino Di Tommaso: Conceptualization, formal analysis, writing -
Review & Editing
Shubhra Sinha: Conceptualization, software, formal analysis, writing -
Review & Editing
Daniel Paul Fudulu: Writing - Review & Editing
Manraj Sandhu: Writing - Review & Editing
Umberto Benedetto: Conceptualization, methodology, supervision
Gianni Angelini: Conceptualization, methodology, writing - Review &
Editing, supervision
Competing interests: None
Funding statement: This study was supported by the British
Heart Foundation and NIHR Biomedical Research Centre at University
Hospitals Bristol and Weston NHS Foundation Trust and the University of
Bristol.
Data Availability statement : All data relevant to the study are
included in the article or uploaded as supplementary information. No
additional data is available.
Ethical approval: All the analysed data was anonymised; hence
there was no need to obtain further ethics approval.
Transparency statement : The lead author affirms that this
manuscript is an honest, accurate, and transparent account of the study
being reported; that no important aspects of the study have been
omitted; and that any discrepancies from the study as planned (and, if
relevant, registered) have been explained.