2.4 Software
The software applications used in the data analyses and data
presentation include:
- NONMEM (version 7.4, ICON Development Solution, MD, US)
- R (version 3.5.3 or higher, The R Foundation for Statistical
Computing, US)
- SAS (version 9.4, SAS Institute, Inc., Cary, NC, US)
- Monolix (Version 2020R1, Lixoft, Antony, France)
The analyses were performed on Intel Xeon-based multi-core Central
Processing Unit servers running Ubuntu 18.04 in Amazon Web Services
(AWS).