3.1 Demographic
The iberdomide popPK analysis dataset included 326 subjects. Table 2 summarized the demographic and baseline disease characteristics of the subjects. There were more male subjects (63.2%) than female (36.8%). Most of the subject were white with a median age of 61 years and median body weight of 76.8 kg. Of note, based on creatinine clearance (CLcr), 45.1% subjects were with normal renal function (CLcr ≥ 90 mL/min), 37.1% subjects were with mild (CLcr 60 to 89 mL/min) and 17.8% moderate (CLcr 30 to 59 mL/min) renal impairment, respectively. Most subjects were with normal hepatic function (93.9%) as per National Cancer Institute organ dysfunction working group criteria.